cIMPACT‐NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

• Published in: Brain pathology (Zurich, Switzerland) Vol. 27; no. 6; pp. 851 - 852
• Main Authors: Louis, David N., Aldape, Ken, Brat, Daniel J., Capper, David, Ellison, David W., Hawkins, Cynthia, Paulus, Werner, Perry, Arie, Reifenberger, Guido, Figarella‐Branger, Dominique, Wesseling, Pieter, Batchelor, Tracy T., Gregory Cairncross, J., Pfister, Stefan M., Rutkowski, Stefan, Weller, Michael, Wick, Wolfgang, von Deimling, Andreas
• Format: Journal Article
• Language: English
• Published: Switzerland John Wiley & Sons, Inc 01-11-2017; Wiley; John Wiley and Sons Inc
• Subjects: Brain cancer; Cancer; Central nervous system; Consortia; Life Sciences; Miscellaneous; Nervous system; Neurobiology; Neurons and Cognition; Taxonomy; Classification of Tumors; neuropathologiste; brain tumors
• ISSN: 1015-6305; 1750-3639
• DOI: 10.1111/bpa.12457

The 2016 World Health Organization Classification of Tumors of the Central Nervous System (2016 CNS WHO) is a major shift in the way neuropathologists analyze and diagnose brain tumors as it incorporates molecular and histological information together to define many entities (1). While the 2016 CNS WHO thereby facilitates more precise diagnosis of well-understood entities and clearer designation of less-understood entities, it also presents a number of practical challenges for neuropathologists, requiring substantial shifts in their day-to-day practices (2). Nonetheless, neuropathologiste will learn the system readily over time, and will adapt as needed to the new requirements.