Molecular basis of spermatogenesis and sperm quality

• Published in: General and comparative endocrinology Vol. 245; pp. 5 - 9
• Main Authors: Robles, Vanesa, Herráez, Paz, Labbé, Catherine, Cabrita, Elsa, Pšenička, Martin, Valcarce, David G, Riesco, Marta F
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-05-2017; Elsevier
• Subjects: Animals; DNA; DNA - genetics; Endocrinology & Metabolism; Epigenesis, Genetic - physiology; Epigenetics; Fishes - genetics; Fishes - physiology; Germ cells; Life Sciences; Male; mRNAs; Non-coding RNAs; RNA - genetics; Sperm quality; Spermatogenesis - genetics; Spermatogenesis - physiology; Spermatozoa - physiology; micro RNA 430; testis specific X-linked gene; RNA; insulin receptor beta; small interfering RNA; ribonucleoproteins; miRISC; zebrafish piwi like RNA-mediated gene silencing 2 homolog; Ct; Spga-lncRNA1; UTR; micro RNA; piwi-interacting RNA; P-element induced wimpy testis; threshold cycle; Sperm quality; qPCR; DCP1a; doublesex and mab-3 related transcription factor; RBP; untranslated region; PGC; BPA; kinesin family member 17 b; dead end protein; miR-430; piRNA; Tsx; long non-coding RNA; MVH; piwi; ribonucleic acid; lncRNA; Germ cells; mRNA; mouse vasa homolog; ICSI; intracytoplasmatic sperm injection; deoxyribonucleic acid; messenger RNA; zili; miRNA; Spga-lncRNA 2; mRNAs; primordial germ cell; CB; Non-coding RNAs; decapping mRNA 1A; Dmr; quantitative polymerase chain reaction; spermatogonia-specificlncRNA 2; siRNA; zebrafish piwi homolog; miRNA-mediated silencing complex; KIF17b; DNA; Insrβ; spermatogonia-specificlncRNA 1; ziwi; Epigenetics; bisphenol A; DND; germ-line cells; trout; poisson; salmonids; adn; mrna; epigenetics; qualité du sperme; Non coding RNAs; rainbow; rainbow trout; mammals; cellule germinale; dna; salmonidae; fish; oncorhynchus mykiss; spermatogenèse; truite arc en ciel; mammifère; germ cells; sperm quality; épigénétique
• ISSN: 0016-6480; 1095-6840
• DOI: 10.1016/j.ygcen.2016.04.026

Highlights • Non-coding RNAs are crucial in the control of germline development. • The chromatoid body (CB) is crucial for successful spermatogenesis. • mRNA profile could be used as a predictor of fertilization ability in fish. • Novel methods allow the quantification of the lesions in particular genome regions. • Environmental or nutritional conditions could modify the epigenetic landmarks.