Aortic dissection and Covid-19; a comprehensive systematic review

• Published in: Current problems in cardiology Vol. 48; no. 6; p. 101129
• Main Authors: Ramandi, Alireza, Akbarzadeh, Mohammad Ali, Khaheshi, Isa, Khalilian, Mohammad Reza
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01-06-2023; Mosby-Year Book
• Subjects: Aortic Dissection - epidemiology; Aortic Dissection - etiology; COVID-19 - complications; Humans; SARS-CoV-2
• ISSN: 0146-2806; 1535-6280; 1535-6280
• DOI: 10.1016/j.cpcardiol.2022.101129

Coronavirus disease 19 (Covid-19) has been declared as a pandemic disease since March 2020; causing wide array of signs and symptoms, many of which result in increased mortality rates worldwide. Although it was initially known as an acute respiratory disease, Covid-19 is accompanied with several extrapulmonary manifestations, of which the cardiovascular ones are of major importance. Among other cardiovascular complications of Covid-19, aortic dissection has been a significant yet underrated problem. The pathophysiology of aortic dissection consists of various inflammatory pathways, that could be influenced by Covid-19 infection. We herein have reviewed articles inclusive of aortic dissection concurrent with Covid-19 infection in a systematic manner, along with the probable similarities in pathophysiology of aortic dissection with Covid-19 infection.