Cystoid Macular Edema in Gyrate Atrophy of the Choroid and Retina: A Fluorescein Angiography and Optical Coherence Tomography Evaluation

• Published in: American journal of ophthalmology Vol. 140; no. 1; pp. 147 - 149
• Main Authors: Oliveira, Tâmara L., Andrade, Rafael E., Muccioli, Cristina, Sallum, Juliana, Belfort, Rubens
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-07-2005; Elsevier; Elsevier Limited
• Subjects: Biological and medical sciences; Cardiovascular system; Child; Choroid - pathology; Fluorescein Angiography - methods; Gyrate Atrophy - complications; Gyrate Atrophy - diagnosis; Humans; Investigative techniques, diagnostic techniques (general aspects); Macular degeneration; Macular Edema - diagnosis; Macular Edema - etiology; Male; Medical research; Medical sciences; Miscellaneous; Ophthalmology; Ornithine - blood; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Retina; Retina - pathology; Retinopathies; Tomography, Optical Coherence - methods; Evaluation; Retinopathy; Radiodiagnosis; Angiography; Cystoid macular edema; Optical coherence tomography; Choroid; Retina; Maculopathy; Atrophy; Eye disease; Fluorescein; Ophthalmology
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2004.12.083

To analyze the importance f optical coherence tomography (OCT) to diagnose the cystoid macular edema in a case of gyrate atrophy.
Observational case report.
A 12-year-old boy presenting with gyrate atrophy of the choroid and retina underwent ophthalmologic, clinical, and laboratory tests.
Plasma ornithine level was 735 μmol/l. Fluorescein angiography showed bilateral hyperfluorescence involving the central region of the macula. Optical coherence tomography (OCT) disclosed bilateral intraretinal cysts areas of low reflectivity with occasional high-signal elements bridging the retinal layers and intraretinal thickening.
Both fluorescein angiography and OCT were helpful to confirm the diagnosis of macular involvement as a complication of gyrate atrophy of the choroid and retina in a patient who presented without any clinical evidence of cystoid macular edema, except a decrease in visual acuity.