Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information

We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreli...

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Bibliographic Details
Published in:	Science China. Life sciences Vol. 58; no. 7; pp. 682 - 686
Main Authors:	Jiang, XinQuan, Zhang, ZhenJie, Zhuang, DongMing, Carr, Michael J., Zhang, RuiLing, Lv, Qiang, Shi, WeiFeng
Format:	Journal Article
Language:	English
Published:	Beijing Science China Press 01-07-2015 Springer Nature B.V
Subjects:	Biomedical and Life Sciences Ebola virus Ebolavirus - genetics Evolution, Molecular Genome, Viral Life Sciences Phylogeny Research Paper 信息参数估计基因数据核苷酸替换病毒基因组系统发育进化非编码区 non-coding region phylogenetic analysis evolutionary information EBOV Ebola
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Summary:	We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.
Bibliography:	We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters. 11-5841/Q EBOV, Ebola, non-coding region, phylogenetic analysis, evolutionary information ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1674-7305 1869-1889
DOI:	10.1007/s11427-015-4857-9