The clinical and immunological features of leprosy

Leprosy is a granulomatous disease affecting the skin and nerves caused by Mycobacterium leprae. It continues to be a significant public health problem. Multidrug therapy (MDT) cures the infection, but immunological reactions may occur and neuropathy may lead to disability and deformity. It is impor...

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Bibliographic Details
Published in:	British medical bulletin Vol. 77-78; no. 1; pp. 103 - 121
Main Authors:	WALKER, S. L, LOCKWOOD, D. N. J
Format:	Journal Article
Language:	English
Published:	Oxford Oxford University Press 01-01-2006 Oxford Publishing Limited (England)
Subjects:	Bacterial diseases Biological and medical sciences Diagnosis, Differential Disabled Persons General aspects Human bacterial diseases Humans Infectious diseases Leprostatic Agents - therapeutic use Leprosy Leprosy - diagnosis Leprosy - drug therapy Leprosy - immunology Medical sciences Mycobacterium leprae Patient Education as Topic Tropical bacterial diseases Infection Medicine Symptomatology Skin disease Bacteriosis Clinical form Leprosy Mycobacterial infection
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Summary:	Leprosy is a granulomatous disease affecting the skin and nerves caused by Mycobacterium leprae. It continues to be a significant public health problem. Multidrug therapy (MDT) cures the infection, but immunological reactions may occur and neuropathy may lead to disability and deformity. It is important that the manifestations of the condition are recognized as early as possible so that early nerve damage can be identified and treated rapidly.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-3 ObjectType-Review-1
ISSN:	0007-1420 1471-8391
DOI:	10.1093/bmb/ldl010