Synthesis of Some Novel Imidazopyrazole and Pyrazolopyrimidine Derivatives

5‐Amino‐3‐anilino‐1H‐pyrazole‐4‐carbonitrile 1 was alkylated with various halo reagents under phase transfer conditions to give the corresponding imidazopyrazole derivatives 2a, 2b, 2c, 3, 4, 5, 6. Pyrazolo[1,5‐a] pyrimidine derivatives 11, 12, 13, 14 were prepared by treating compound 1 with differ...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry Vol. 51; no. 5; pp. 1476 - 1481
Main Authors: Soliman, Ahmed M. M., El-Remaily, Mahmoud. Abd El-Aleem. Ali. Ali, Sultan, Adel. A., Abdel-Ghany, Hossam
Format: Journal Article
Language:English
Published: Hoboken Blackwell Publishing Ltd 01-09-2014
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Summary:5‐Amino‐3‐anilino‐1H‐pyrazole‐4‐carbonitrile 1 was alkylated with various halo reagents under phase transfer conditions to give the corresponding imidazopyrazole derivatives 2a, 2b, 2c, 3, 4, 5, 6. Pyrazolo[1,5‐a] pyrimidine derivatives 11, 12, 13, 14 were prepared by treating compound 1 with different dicarbonyl reagents, namely, diethymalonate, ethyl 3‐oxo‐3‐phenylpropanoate, pentane‐2,4‐dione or ethyl 3‐oxobutanoate.
Bibliography:ark:/67375/WNG-B0D3J6S0-V
ArticleID:JHET1701
istex:B6CF738DE8C2D245A071688B840F6AEDA875BBBE
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.1701