Cervical myelopathy caused by ventrally located atlanto-axial synovial cysts: An open quest for the safest and most effective surgical management. Case series and systematic review of the literature

• Published in: Neuro-chirurgie Vol. 66; no. 6; pp. 447 - 454
• Main Authors: Chibbaro, S., Gubian, A., Zaed, I., Hajhouji, F., Pop, R., Todeschi, J., Bernard, G., Di Emidio, P., Mallereau, C.-H., Proust, F., Ganau, M.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01-12-2020
• Subjects: Aged; Atlanto-Axial Joint; C1-C2; Cervical Vertebrae - pathology; Cervical Vertebrae - surgery; Cranio-cervical junction; Female; Humans; Joint Instability - surgery; Male; Middle Aged; Neurosurgical Procedures - methods; Posterior approach; Shoulder Pain - etiology; Shoulder Pain - surgery; Spinal Cord Diseases - pathology; Spinal Cord Diseases - surgery; Surgery; Synovial Cyst - pathology; Synovial Cyst - surgery; Synovial cysts; Treatment Outcome; SCs; NS; MRI; F; C1-C2; M; SSEPs; CT; Cranio-cervical junction; Surgery; CSF; Synovial cysts; mJOA; Posterior approach; EMG; MEPs; mL
• ISSN: 0028-3770; 1773-0619
• DOI: 10.1016/j.neuchi.2020.09.007

Despite a good understanding of the natural history of spinal synovial cysts (SCs), a widespread agreement regarding their optimal management is still lacking. This is particularly true for SCs occurring at the C1-C2 level, which are rare, but oftentimes lead to a rapidly evolving cervical myelopathy.
We report a series of 4 patients (M:F ratio=1:1; mean age 63.5 years) presenting with progressive cervical myelopathy secondary to ventrally located C1-C2 SCs. All patients underwent a postero-lateral facet-sparing intradural approach with total excision of the SCs. Functional status was assessed pre- and postoperatively with Nurick scale and the modified Japanese Orthopaedic association grading. Furthermore we conducted a systematic review, following PRISMA guidelines of pertinent literature to contextualize the options for surgical management of such lesions.
Complete excision of the SCs was confirmed radiologically and on histological analysis. All measures of functional status improved post-operatively, and no cyst recurrence or need for instrumented fusion were noted during follow up (range from 22 to 88 months).
Our experience suggests that the facet-sparing intradural approach provides excellent clinical outcomes without causing any C1–C2 instability. This is in keeping with the take home message emerging from our literature review, which confirms that treatment should aim at radical resection of SCs while minimizing the risk of postoperative instability.