Daily Predictors of ART Adherence Among Young Men Living with HIV Who Have Sex with Men: A Longitudinal Daily Diary Study

• Published in: AIDS and behavior Vol. 26; no. 6; pp. 1727 - 1738
• Main Authors: Cherenack, Emily M., Enders, Kimberly, Rupp, Betty M., Seña, Arlene C., Psioda, Matthew
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-06-2022; Springer Nature B.V
• Subjects: Antiretroviral agents; Antiretroviral drugs; Antiretroviral therapy; Autobiographical literature; Cannabis; Data collection; Diaries; Drug use; Emotions; Gays & lesbians; Health behavior; Health Psychology; HIV; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV Infections - psychology; Human immunodeficiency virus; Humans; Infectious Diseases; Male; Marijuana; Medication Adherence - psychology; Medicine; Medicine & Public Health; Mens health; Original Paper; Patient compliance; Psychosocial factors; Public Health; Retrospective Studies; Sex; Sexual and Gender Minorities; Sexual intercourse; Sexually transmitted diseases; Social interactions; Social support; STD; Stress; Substance abuse; Substance use; Substance-Related Disorders - complications; Substance-Related Disorders - epidemiology; Teenagers; United States - epidemiology; Young adults; Young men; United States; HIV/AIDS; Adherence; Young men who have sex with men; Adolescents; Daily diaries
• ISSN: 1090-7165; 1573-3254
• DOI: 10.1007/s10461-021-03523-2

Improving adherence to antiretroviral therapy (ART) is essential for limiting HIV disease progression among young sexual minority men living with HIV. Daily diaries allow for a detailed examination of how fluctuations in psychosocial factors are associated with adherence over time. Across three cities in the United States, this study collected 60 days of quantitative data from 44 young men (between 16 and 24 years of age) living with HIV who have sex with men. Lagged transition models explored the associations of mood, stress, social support, substance use, and condomless intercourse with daily ART adherence. Baseline levels of illicit substance use and condomless intercourse, and a higher proportion of days with stress or marijuana use, were associated with lower ART adherence. Lapses in adherence predicted non-adherence the following day. Findings suggest prospective data collection may identify different predictors of adherence compared to retrospective recall. Lapse-management strategies are needed to improve adherence following a missed dose.