Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype

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Bibliographic Details
Published in:	Haematologica (Roma) Vol. 103; no. 1; pp. e17 - e20
Main Authors:	Rücker, Frank G, Dolnik, Anna, Blätte, Tamara J, Teleanu, Veronica, Ernst, Aurélie, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars
Format:	Journal Article
Language:	English
Published:	Italy Ferrata Storti Foundation 01-01-2018
Subjects:	Abnormal Karyotype Biomarkers, Tumor Cell Cycle - genetics Chromothripsis Genetic Association Studies Genetic Predisposition to Disease Humans Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - pathology Mutation Online Only Polymorphism, Single Nucleotide Prognosis Tumor Suppressor Protein p53 - genetics
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Bibliography:	SourceType-Other Sources-1 ObjectType-Article-2 content type line 63 ObjectType-Correspondence-1 KD and LB contributed equally to this work.
ISSN:	0390-6078 1592-8721
DOI:	10.3324/haematol.2017.180497