Hyperparathyroidism‐jaw tumour syndrome

• Published in: Journal of internal medicine Vol. 253; no. 6; pp. 634 - 642
• Main Authors: Chen, J. D., Morrison, C., Zhang, C., Kahnoski, K., Carpten, J. D., Teh, B. T.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01-06-2003; Blackwell Science; Blackwell Publishing Ltd
• Subjects: Biological and medical sciences; Endocrinopathies; Genes, Tumor Suppressor; HRPT2; Humans; hyperparathyroidism; Hyperparathyroidism - genetics; Hyperparathyroidism - pathology; Jaw Neoplasms - genetics; Jaw Neoplasms - pathology; jaw tumour; Kidney Neoplasms - genetics; Kidney Neoplasms - pathology; Maxillary Neoplasms - genetics; Maxillary Neoplasms - pathology; Medical sciences; Multiple Endocrine Neoplasia Type 1; Non tumoral diseases. Target tissue resistance. Benign neoplasms; Parafibromin; Parathyroid Neoplasms - pathology; Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases); Syndrome; Endocrinopathy; Human; jaw tumour; Jaw; Review; Pathology; Symptomatology; Histopathology; Parathyroid diseases; Tumor; HRPT2; Diagnosis; Hyperparathyroidism; Parafibromin
• ISSN: 0954-6820; 1365-2796
• DOI: 10.1046/j.1365-2796.2003.01168.x

.  Chen JD, Morrison C, Zhang C, Kahnoski K, Carpten JD, Teh BT (Van Andel Research Institute, Grand Rapids, MI; Ohio State University Comprehensive Cancer Center, Columbus, OH; and National Human Genome Research Institute, National Insitutes of Health, Bethesda, MD, USA). Hyperparathyroidism‐jaw tumour syndrome (Minisymposium). J Intern Med 2003; 253: 634–642.
Amongst hyperparathyroidism‐related syndromes, hyperparathyroidism‐jaw tumour syndrome is one of the least common and relatively unknown but its clinical and genetic aspects are not less interesting or important. With the recent identification of its genes, we can now better characterize the disease, both clinically and genetically, which will certainly impact the field of endocrinology and oncology. In this article, we review the clinico‐pathological features and genetic basis of this syndrome with the hope that it will create awareness and interest in this disease amongst clinicians and basic scientists.