Poly(vinyl alcohol)/Plant Extracts Films: Preparation, Surface Characterization and Antibacterial Studies against Gram Positive and Gram Negative Bacteria

• Published in: Materials Vol. 15; no. 7; p. 2493
• Main Authors: Barbălată-Mândru, Mihaela, Serbezeanu, Diana, Butnaru, Maria, Rîmbu, Cristina Mihaela, Enache, Alexandru Alin, Aflori, Magdalena
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28-03-2022; MDPI
• Subjects: Bacteria; Biocompatibility; Biomedical materials; Cannabis; Cannabis sativa L; Contact angle; E coli; extract of Lavandula angustifolia; Flavonoids; Fourier transforms; Hemp; Herbal medicine; Infrared analysis; Infrared reflection; Marijuana; Mentha piperita; Metabolites; Microorganisms; Peppermint; Phenols; Phytochemicals; Plants (botany); poly(vinyl alcohol); Polymers; Polyvinyl alcohol; Salvia officinalis folium; Staphylococcus infections; Steroids; Surface properties; Toxicity; Verbena officinalis; St Louis Missouri; United States > US; Germany; Verbena officinalis; antibacterial activity; Mentha piperita; Cannabis sativa L; poly(vinyl alcohol); extract of Lavandula angustifolia; Salvia officinalis folium; cytotoxicity
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma15072493

In this study, we aim to obtain biomaterials with antibacterial properties by combining poly(vinyl alcohol) with the extracts obtained from various selected plants from Romania. Natural herbal extracts of freshly picked flowers of the lavender plant (
) and leaves of the peppermint plant (
hemp plant (
L.), verbena plant
and sage plant
were selected after an intensive analyzing of diverse medicinal plants often used as antibacterial and healing agents from the country flora. The plant extracts were characterized by different methods such as totals of phenols and flavonoids content and UV-is spectroscopy. The highest amounts of the total phenolic and flavonoid contents, respectively, were recorded for
Moreover, the obtained films of poly(vinyl alcohol) (PVA) loaded with plant extracts were studied concerning the surface properties and their antibacterial or cytotoxicity activity. The Attenuated Total Reflection Fourier Transform Infrared analysis described the successfully incorporation of each plant extract in the poly(vinyl alcohol) matrix, while the profilometry demonstrated the enhanced surface properties. The results showed that the plant extracts conferred significant antibacterial effects to films toward
and
and are not toxic against fibroblastic cells from the rabbit.