Microwave-enhanced cross-coupling reactions involving alkynyltrifluoroborates with aryl bromides

Palladium-catalyzed alkynylation has emerged as one of the most reliable methods for the synthesis of alkynes which are often used in natural product syntheses and material science. An efficient method for coupling alkynyltrifluoroborates with various aryl bromides in the presence of a palladium cat...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 18; no. 2; pp. 1755 - 1761
Main Authors:	Coltuclu, Vitali, Dadush, Eric, Naravane, Abhijit, Kabalka, George W
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 29-01-2013 MDPI
Subjects:	alkynes BASIC BIOLOGICAL SCIENCES Borates - chemistry Bromides - chemistry Chemistry, Organic - methods Chromatography coupling reactions INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY microwave Microwaves Natural products organotrifluoroborates Palladium Potassium Reagents United States > US
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Summary:	Palladium-catalyzed alkynylation has emerged as one of the most reliable methods for the synthesis of alkynes which are often used in natural product syntheses and material science. An efficient method for coupling alkynyltrifluoroborates with various aryl bromides in the presence of a palladium catalyst has been developed using microwave irradiation. The microwave reactions are rapid and efficient.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Frontier Scientific Inc. USDOE Robert H. Cole Foundation
ISSN:	1420-3049 1420-3049
DOI:	10.3390/molecules18021755