A Defined N-Heterocyclic Carbene Complex for the Palladium-Catalyzed Suzuki Cross-Coupling of Aryl Chlorides at Ambient Temperatures

Highly active but sterically demanding: Ambient‐temperature Suzuki cross‐coupling of aryl chlorides is possible with a palladium(0) complex bearing two bulky, N‐heterocyclic carbene ligands (see structure). Nearly quantitative yields are obtained within two hours with some reagents, which makes this...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 41; no. 8; pp. 1363 - 1365
Main Authors:	Gstöttmayr, Christian W. K., Böhm, Volker P. W., Herdtweck, Eberhardt, Grosche, Manja, Herrmann, Wolfgang A.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag GmbH 15-04-2002 WILEY‐VCH Verlag GmbH
Subjects:	carbene ligands carbenes C−C coupling homogeneous catalysis palladium
Online Access:	Get full text
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Summary:	Highly active but sterically demanding: Ambient‐temperature Suzuki cross‐coupling of aryl chlorides is possible with a palladium(0) complex bearing two bulky, N‐heterocyclic carbene ligands (see structure). Nearly quantitative yields are obtained within two hours with some reagents, which makes this compound the most active catalyst known to date under these conditions.
Bibliography:	istex:CB97A2576B011D12455EADE4D27DEC1722E1AC82 ark:/67375/WNG-P2QQW93C-M ArticleID:ANIE1363 N‐Heterocyclic Carbenes, Part 32. This work was supported by the Deutsche Forschungsgemeinschaft (DFG), the Bayerischer Forschungsverbund Katalyse (FORKAT), and Bayer AG. We thank Dr. Öfele and Dr. Scholz for helpful discussion. Part 31 ref. [4c] (review in this issue). ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1433-7851 1521-3773
DOI:	10.1002/1521-3773(20020415)41:8<1363::AID-ANIE1363>3.0.CO;2-G