Influence of bone densitometry on the anti-osteoporosis treatment after fragility hip fracture

• Published in: Aging clinical and experimental research Vol. 31; no. 10; pp. 1525 - 1529
• Main Authors: Wang, Peiwen, Li, Yizhong, Zhuang, Huafeng, Yu, Haiming, Cai, Siqing, Xu, Hao, Chen, Zhenhui, Lin, Jinkuang, Yao, Xuedong
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01-10-2019; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Bone Density; Diphosphonates - therapeutic use; Female; Femur; Femur Neck; Fractures; Geriatrics/Gerontology; Hip Fractures - complications; Hospitalization; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Original; Original Article; Osteoporosis; Osteoporosis - drug therapy; Osteoporosis - prevention & control; Retrospective Studies; Secondary Prevention; Osteoporosis; Hip fracture; Treatment; Bone mineral density assessment
• ISSN: 1720-8319; 1594-0667; 1720-8319
• DOI: 10.1007/s40520-018-1094-7

Background
Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many patients with hip fracture do not receive osteoporosis treatment. This retrospective study investigates the influence of bone mineral density (BMD) assessment on the initiation of anti-osteoporosis medications in the hospitalized patients with fragility hip fracture.
Methods
This retrospective research enrolled 1211 patients with fragility hip fracture 50 years of age and older. Among 1211 patients aged from 50 to 103 years with the average age of 77.83 ± 9.95 years, there were 807 females and 404 males. There were 634 fractures of femoral neck and 577 intertrochanteric fractures of femur. We examined whether patients had received bone mineral density assessment and received anti-osteoporosis therapy during the period of hospitalization. The patients were divided into BMD assessment group and no BMD assessment group. Measurement data were expressed as mean ± standard deviation and compared with
t
test. All parameters of groups were compared with Chi-square test.
Results
Of 1211 patients, 331 (27.33%) had received BMD assessment and 925 (76.38%) had received anti-osteoporosis drugs during the period of hospitalization. The rate of bisphosphonate use was lower and only 11.31% in the total patients. The anti-osteoporosis treatment rate was 93.66% in the patients receiving BMD assessment and 69.89% in the patients without BMD assessment (
p
 < 0.01). The zoledronate use significantly increased from 6.7% in the patients without BMD assessment to 23.56% in the patients receiving BMD assessment (
p
 < 0.01).
Conclusions
BMD assessment is a good basis for communication between patients and orthopedic surgeons. BMD assessment significantly increases the initiation of osteoporosis treatment and bisphosphonate use in the patients with hip fracture during the period of hospitalization.