Thermoheliox: effect on the functional hemodynamics of the human brain

• Published in: Russian chemical bulletin Vol. 71; no. 3; pp. 591 - 594
• Main Authors: Varfolomeev, S. D., Panin, A. A., Semenova, N. A., Ublinskiy, M. V., Akhadov, T. A., Bykov, V. I., Tsybenova, S. B.
• Format: Journal Article
• Language: English
• Published: New York Springer US 2022; Springer Nature B.V
• Subjects: Brain; Brief Communications; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Empirical equations; Hemodynamic responses; Hemodynamics; Inorganic Chemistry; Magnetic resonance imaging; Organic Chemistry; Respiration; Vasoconstriction; Visual stimuli; BOLD-effect; kinetics; visual stimulus; thermoheliox; functional magnetic resonance imaging
• ISSN: 1066-5285; 1573-9171
• DOI: 10.1007/s11172-022-3455-9

A kinetic study of the effect of thermoheliox (inhalation of a helium and oxygen mixture, 70 °C) on the functional hemodynamics of the human brain by functional magnetic resonance imaging was carried out. The dynamic responses of the BOLD signal were found to be biphasic. An empirical equation describing the first phase of the hemodynamic response to visual stimulus was proposed. It was shown that preliminary inhalation of thermoheliox stimulates the hemodynamic responses by slowing down the vasoconstriction.