Public-Private Partnership: A New Engine for Translational Research in Neurosciences

We have made little recent progress developing effective new treatments for neuropsychiatric and neurodevelopmental disorders. Novel molecular mechanisms have been identified, but have not translated into the clinic. We suggest an alternative: combinations of treatments targeting different aspects o...

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Bibliographic Details
Published in:	Neuron (Cambridge, Mass.) Vol. 84; no. 3; pp. 533 - 536
Main Authors:	Murphy, Declan G.M., Goldman, Michel, Loth, Eva, Spooren, Will
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 05-11-2014 Elsevier Limited
Subjects:	Autism Behavior Biomarkers Brain research Cancer Cancer therapies Humans Medical research Mental Disorders - diagnosis Mental Disorders - therapy Nervous System Diseases - diagnosis Nervous System Diseases - therapy Neurosciences Neurosciences - methods Neurosciences - trends Pharmaceutical industry Public-Private Sector Partnerships Regulatory approval Rodents Studies Translational Medical Research - methods Translational Medical Research - trends United States > US
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Summary:	We have made little recent progress developing effective new treatments for neuropsychiatric and neurodevelopmental disorders. Novel molecular mechanisms have been identified, but have not translated into the clinic. We suggest an alternative: combinations of treatments targeting different aspects of final common pathways in biologically defined clinical subgroups. This will require integrated translational neuroscience and international public-private partnerships.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0896-6273 1097-4199
DOI:	10.1016/j.neuron.2014.10.006