Sequences of memory-guided saccades in Parkinson's disease
Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was imp...
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Published in: | Annals of neurology Vol. 35; no. 4; p. 487 |
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Main Authors: | , , , , , , |
Format: | Journal Article |
Language: | English |
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01-04-1994
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Abstract | Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was impaired in patients in the "off" state, but significantly improved during the "on" period. These results are compatible with a decreased activation of the supplementary motor area, which can be reversed by levodopa. |
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AbstractList | Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was impaired in patients in the "off" state, but significantly improved during the "on" period. These results are compatible with a decreased activation of the supplementary motor area, which can be reversed by levodopa. |
Author | Vermersch, A I Pierrot-Deseilligny, C Bonnet, A M Rivaud, S Gaymard, B Vidailhet, M Agid, Y |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/8154878$$D View this record in MEDLINE/PubMed |
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Snippet | Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude... |
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SubjectTerms | Electrooculography Humans Memory - physiology Middle Aged Parkinson Disease - physiopathology Photic Stimulation Reaction Time - physiology Saccades - physiology |
Title | Sequences of memory-guided saccades in Parkinson's disease |
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