Sequences of memory-guided saccades in Parkinson's disease

Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was imp...

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Published in:Annals of neurology Vol. 35; no. 4; p. 487
Main Authors: Vermersch, A I, Rivaud, S, Vidailhet, M, Bonnet, A M, Gaymard, B, Agid, Y, Pierrot-Deseilligny, C
Format: Journal Article
Language:English
Published: United States 01-04-1994
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Abstract Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was impaired in patients in the "off" state, but significantly improved during the "on" period. These results are compatible with a decreased activation of the supplementary motor area, which can be reversed by levodopa.
AbstractList Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude of single saccades was decreased and not improved by treatment. The chronology of saccades during sequences was impaired in patients in the "off" state, but significantly improved during the "on" period. These results are compatible with a decreased activation of the supplementary motor area, which can be reversed by levodopa.
Author Vermersch, A I
Pierrot-Deseilligny, C
Bonnet, A M
Rivaud, S
Gaymard, B
Vidailhet, M
Agid, Y
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  surname: Pierrot-Deseilligny
  fullname: Pierrot-Deseilligny, C
BackLink https://www.ncbi.nlm.nih.gov/pubmed/8154878$$D View this record in MEDLINE/PubMed
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Snippet Sequences of ocular saccades were studied in 8 patients with Parkinson's disease, with (i.e., "on") and without (i.e., "off") levodopa treatment. The amplitude...
SourceID pubmed
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StartPage 487
SubjectTerms Electrooculography
Humans
Memory - physiology
Middle Aged
Parkinson Disease - physiopathology
Photic Stimulation
Reaction Time - physiology
Saccades - physiology
Title Sequences of memory-guided saccades in Parkinson's disease
URI https://www.ncbi.nlm.nih.gov/pubmed/8154878
Volume 35
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