Oral immunization against porcine pleuropneumonia using the cubic phase of monoolein and purified toxins of Actinobacillus pleuropneumoniae

• Published in: Vaccine Vol. 32; no. 50; pp. 6805 - 6811
• Main Authors: Lopez-Bermudez, Jorge, Quintanar-Guerrero, David, Lara Puente, Horacio, Tórtora Perez, Jorge, Suárez Güemez, Francisco, Ciprián Carrasco, Abel, Mendoza Elvira, Susana
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 28-11-2014; Elsevier
• Subjects: Actinobacillus Infections - prevention & control; Actinobacillus Infections - veterinary; Actinobacillus pleuropneumoniae; Actinobacillus pleuropneumoniae - immunology; Administration, Oral; Allergy and Immunology; Animals; Applied microbiology; Apx I; Apx II; Apx III; Bacterial Toxins - administration & dosage; Bacterial Toxins - immunology; Bacterial Toxins - isolation & purification; Bacteriology; Biological and medical sciences; Drug Carriers - administration & dosage; Fundamental and applied biological sciences. Psychology; Glycerides - administration & dosage; Histocytochemistry; Immunity; Immunization - methods; Lung - microbiology; Lung - pathology; Microbiology; Miscellaneous; Oral vaccine; Palatine Tonsil - microbiology; Pleuropneumonia - prevention & control; Pleuropneumonia - veterinary; Porcine pleuropneumonia; Spleen - microbiology; Swine; Swine Diseases - prevention & control; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Porcine pleuropneumonia; Apx I; Oral vaccine; Apx II; Apx III; Immunity; Immunization; Vaccine; Pasteurellaceae; Toxin; Vertebrata; Mammalia; Swine; Bacteria; Artiodactyla; Actinobacillus pleuropneumoniae; Veterinary; Ungulata
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2014.09.056

Highlights • The immunogen proposed does not need special storage conditions. • The immunogen have a good immunization for CPP in pigs. • Provide protection against CPP by oral route. • It decreased the pig stress produced by parenteral treatments.