Epilepsy and microRNA

Highlights ► First review on microRNA and epilepsy. ► Rich background to the topic for the non-specialist. ► Comprehensive review of published microRNA research in the field to date. ► Future prospects. ► Figure and Table to illustrate key points and discoveries.

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Bibliographic Details
Published in:	Neuroscience Vol. 238; pp. 218 - 229
Main Authors:	Jimenez-Mateos, E.M, Henshall, D.C
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 15-05-2013
Subjects:	Animals apoptosis dicer Disease Models, Animal epigenetics Epilepsy - genetics Epilepsy - metabolism Epilepsy - pathology epileptogenesis hippocampal sclerosis Hippocampus - metabolism Hippocampus - pathology Humans MicroRNAs - genetics MicroRNAs - metabolism Neurology Neurons - metabolism Neurons - pathology non-coding RNA Sclerosis - genetics Sclerosis - metabolism Sclerosis - pathology temporal lobe epilepsy doublecortin toll-like receptors non-coding RNA apoptosis HMGB1 TLE epigenetics UTR high mobility group box 1 intracerebroventricular miRNA dicer RISC temporal lobe epilepsy Argonaute proteins hippocampal sclerosis Ago untranslated region Lim-domain containing kinase 1 RNA-induced silencing complex Locked-nucleic acid MicroRNA Limk1 epileptogenesis DCX i.c.v LNA TLRs
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Summary:	Highlights ► First review on microRNA and epilepsy. ► Rich background to the topic for the non-specialist. ► Comprehensive review of published microRNA research in the field to date. ► Future prospects. ► Figure and Table to illustrate key points and discoveries.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2013.02.027