Trisomy 10 mosaicism in a newborn boy; delineation of the syndrome

Trisomy 10 mosaicism in a newborn boy; delineation of the syndrome

The fifth case of trisomy 10 mosaicism is presented. Only in cultured fibroblasts this mosaicism was found, while peripheral lymphocytes revealed a normal karyotype. In comparison with the literature, trisomy 10 mosaicism syndrome is further delineated compromising of failure to thrive, high forehea...

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Bibliographic Details
Published in:Clinical genetics Vol. 27; no. 1; p. 92
Main Authors: de France, H F, Beemer, F A, Senders, R C, Schaminée-Main, S C
Format: Journal Article
Language:English
Published: Denmark 01-01-1985
Subjects:
Abnormalities, Multiple - genetics
Chromosomes, Human, 6-12 and X
Fibroblasts - ultrastructure
Humans
Infant, Newborn
Lymphocytes - ultrastructure
Male
Mosaicism
Trisomy
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Summary:The fifth case of trisomy 10 mosaicism is presented. Only in cultured fibroblasts this mosaicism was found, while peripheral lymphocytes revealed a normal karyotype. In comparison with the literature, trisomy 10 mosaicism syndrome is further delineated compromising of failure to thrive, high forehead, hypertelorism, mongoloid eye slant, blepharophimosis, dysplastic, large ears, retrognathia, long slender trunk, marked plantar and palmar furrows, cardiopathy and early death.
ISSN:0009-9163
DOI:10.1111/j.1399-0004.1985.tb00190.x