Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation

• Published in: Transplant infectious disease Vol. 13; no. 4; pp. 419 - 423
• Main Authors: Rosow, L., Jiang, J.X., Deuel, T., Lechpammer, M., Zamani, A.A., Milner, D.A., Folkerth, R., Marty, F.M., Kesari, S.
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01-08-2011
• Subjects: Antifungal Agents - therapeutic use; Ascomycota - classification; Ascomycota - drug effects; Ascomycota - isolation & purification; Bipolaris spicifera; brain abscess; Brain Abscess - diagnostic imaging; Brain Abscess - drug therapy; Brain Abscess - microbiology; Cerebral Phaeohyphomycosis - diagnostic imaging; Cerebral Phaeohyphomycosis - drug therapy; Cerebral Phaeohyphomycosis - microbiology; heart transplantation; Heart Transplantation - adverse effects; Humans; Immunocompromised Host; immunosuppression; Magnetic Resonance Imaging; Male; Middle Aged; Mycoses - diagnostic imaging; Mycoses - drug therapy; Mycoses - microbiology; phaeohyphomycosis; Pyrimidines - therapeutic use; Radiography; Treatment Outcome; Triazoles - therapeutic use; Voriconazole
• ISSN: 1398-2273; 1399-3062
• DOI: 10.1111/j.1399-3062.2011.00610.x

L. Rosow, J.X. Jiang, T. Deuel, M. Lechpammer, A.A. Zamani, D.A. Milner, R. Folkerth, F.M. Marty, S. Kesari. Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation.
Transpl Infect Dis 2011: 13: 419–423. All rights reserved
: Phaeohyphomycosis is an increasingly recognized cause of brain abscess in both immunocompetent and immunocompromised hosts. We report a case of cerebral phaeohyphomycosis in a 55‐year‐old male heart transplant recipient caused by Bipolaris spicifera. We review the literature regarding the pathogenesis, epidemiology, diagnosis, and management of infections with dematiaceous fungi.