Feasibility, Acceptability, and Clinical Significance of a Dyadic, Web-Based, Psychosocial and Physical Activity Self-Management Program ( TEMPO ) Tailored to the Needs of Men with Prostate Cancer and Their Caregivers: A Multi-Center Randomized Pilot Trial

• Published in: Current oncology (Toronto) Vol. 29; no. 2; pp. 785 - 804
• Main Authors: Lambert, Sylvie D, Duncan, Lindsay R, Culos-Reed, S Nicole, Hallward, Laura, Higano, Celestia S, Loban, Ekaterina, Katz, Anne, De Raad, Manon, Ellis, Janet, Korman, Melissa B, Sears, Carly, Ibberson, Cindy, Walker, Lauren, Belzile, Eric, Saha-Chaudhuri, Paramita, McTaggart-Cowan, Helen, Peacock, Stuart
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 01-02-2022; MDPI AG
• Subjects: behavior change; caregivers; Caregivers - psychology; Cyclic N-Oxides; e-Health interventions; Exercise; Feasibility Studies; Humans; Internet; Male; physical activity; Pilot Projects; prostate cancer; Prostatic Neoplasms - therapy; Quality of Life - psychology; Self-Management; caregivers; dyads; prostate cancer; dyadic interventions; pilot study; e-Health interventions; psychosocial needs; behavior change; self-management; physical activity
• ISSN: 1718-7729; 1198-0052; 1718-7729
• DOI: 10.3390/curroncol29020067

Prostate cancer is the most common cancer diagnosis among men. Family caregivers (often female spouses) play a key role in ensuring patients' needs are met, frequently assuming their role with no formal training, which can contribute to a high burden. The purpose of this study was to pilot
-the first dyadic, Tailored, wEb-based, psychosocial and physical activity self-Management PrOgram for men with prostate cancer and their caregivers.
49 men with prostate cancer and their caregivers were randomized to
or usual care. Baseline and follow-up questionnaires were completed to assess feasibility, acceptability, and clinical significance. A priori benchmarks for these outcomes were set. Thirteen exit interviews were conducted to further explore acceptability.
Feasibility benchmarks were met with the exception for recruitment with on average 6.1 dyads recruited/month (benchmark: 8 dyads/month). Benchmarks of acceptability focused on attrition (<25%) and system usability, which were met. Using the strict criteria for adherence of 100% of the module viewed and participants spending at least 15 min on the module, 45% of participants were adherent. The clinical significance on anxiety and quality of life was supported for caregivers, and mostly supported for the men with prostate cancer.
This pilot trial was successful, with minor modifications needed prior to a large trial.