Pulmonological issues

Pediatric leukodystrophies are rare neurodegenerative diseases involving multiple systems. Each form has unique neurologic features but are characterized by encephalopathy with accompanying impairments evidenced in reflexes, muscle tone and movement control. Weakness of expiratory, inspiratory, and...

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Bibliographic Details
Published in:	Current problems in pediatric and adolescent health care Vol. 52; no. 12; p. 101313
Main Authors:	Perez, Geovanny, Young, Lisa, Kravitz, Richard, Sheehan, Daniel, Adang, Laura, Van Haren, Keith, Lin, Jody L., Jaffe, Nicole Nikki, Kuo, Dennis, Ball, Laura, Keller, Jennifer, Sank, Jeffrey, DiVito, Donna, Naime, Samira
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-12-2022
Subjects:	Child Humans Sleep Apnea Syndromes
Online Access:	Get full text
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Summary:	Pediatric leukodystrophies are rare neurodegenerative diseases involving multiple systems. Each form has unique neurologic features but are characterized by encephalopathy with accompanying impairments evidenced in reflexes, muscle tone and movement control. Weakness of expiratory, inspiratory, and upper airway muscles may lead to impaired airway secretion clearance resulting in recurrent respiratory infections, dysphagia, sleep-disordered breathing, restrictive lung disease, and ultimately chronic respiratory insufficiency.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1538-5442 1538-3199 1538-3199
DOI:	10.1016/j.cppeds.2022.101313