Isolated Acute Cellular Rejection of the Liver After Simultaneous Liver and Kidney Transplantation: A Case Report

• Published in: Transplantation proceedings Vol. 40; no. 8; pp. 2832 - 2834
• Main Authors: Nah, Y.W, Nam, C.W, Suh, J.H, Cha, H.J, Kim, G.Y, Park, S.J, Oh, Y, Cho, H.R
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01-10-2008; Elsevier
• Subjects: Acute Disease; Biological and medical sciences; Biopsy; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Rejection - diagnosis; Humans; Immunosuppressive Agents - therapeutic use; Inflammation; Kidney Transplantation - immunology; Kidney Transplantation - pathology; Liver Circulation; Liver Transplantation - immunology; Liver, biliary tract, pancreas, portal circulation, spleen; Male; Medical sciences; Methylprednisolone Hemisuccinate - therapeutic use; Middle Aged; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Surgery of the urinary system; Tissue, organ and graft immunology; Treatment Outcome; Human; Graft(material); Digestive system; Acute; Liver; Concurrent; Homotransplantation; Kidney; Case study; Medicine; Rejection; Treatment; Urinary system; Surgery; Graft; Cell; Kidney transplantation; Liver transplantation
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2008.08.021

Abstract Simultaneous liver and kidney transplantation (SLKT) is now considered the treatment of choice for patients with concurrent end-stage liver and kidney diseases. Even though the early postoperative mortality rate following SLKT is reported to be high compared to that of liver transplantation alone, the liver graft from the same donor has been argued to induce better kidney graft acceptance as evidenced by a low rate of acute renal rejection episodes. There have been many reports of a low incidence of acute renal rejection following SLKT; however, only a few cases were proven by simultaneous biopsies. The authors experienced a case of biopsy-proven isolated acute cellular rejection of the liver graft following SLKT.