Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures

• Published in: Case reports in pediatrics Vol. 2015; no. 2015; pp. 1 - 3
• Main Authors: Aydın, Kürşad, Hirfanoğlu, Tuğba, Çıtak Kurt, Ayşegül Neşe, Kartal, Ayşe, Serdaroğlu, Ayşe
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01-01-2015; Hindawi Limited
• Subjects: Case Report
• ISSN: 2090-6803; 2090-6811
• DOI: 10.1155/2015/783936

Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis.