Acute fibrinous and organizing pneumonia

A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin "balls" deposits and focal features of organizing pneumonia, both of which are typical pathological fe...

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Published in:	Annals of Saudi medicine Vol. 33; no. 3; pp. 301 - 303
Main Authors:	Al-Khouzaie, Thamer H, Dawamneh, Mohamad F, Hazmi, Albader M
Format:	Journal Article
Language:	English
Published:	Saudi Arabia KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE 01-05-2013 King Faisal Specialist Hospital and Research Centre
Subjects:	Acute Disease Arthralgia - etiology Biopsy Blood tests Case Report Consolidation Cryptogenic Organizing Pneumonia - diagnosis Cryptogenic Organizing Pneumonia - drug therapy Cryptogenic Organizing Pneumonia - pathology Dyspnea Dyspnea - etiology Family medical history Fever Glucocorticoids - therapeutic use HIV Human immunodeficiency virus Humans Leukemia Lungs Male Medical imaging Middle Aged Neutrophils Pathology Patients Pneumonia Prednisone - therapeutic use Severe acute respiratory syndrome Stem cells Tomography, X-Ray Computed Transplants & implants Treatment Outcome Saudi Arabia Singapore
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Abstract	A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin "balls" deposits and focal features of organizing pneumonia, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). The patient had a good clinical course after treatment with prednisone. We report this case of idiopathic AFOP and review the published studies on this newly recognized clinicopathological entity that is still underdiagnosed and underreported.
AbstractList	A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin “balls” deposits and focal features of organizing pneumonia, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). The patient had a good clinical course after treatment with prednisone. We report this case of idiopathic AFOP and review the published studies on this newly recognized clinicopathological entity that is still underdiagnosed and underreported.
Author	Hazmi, Albader M Dawamneh, Mohamad F Al-Khouzaie, Thamer H
AuthorAffiliation	b Pathology Service Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia c Radiology Service Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia a Internal Medicine Services Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia
AuthorAffiliation_xml	– name: a Internal Medicine Services Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia – name: c Radiology Service Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia – name: b Pathology Service Division, Saudi Aramco Medical Services Organization (SAMSO), Dhahran Health Center (DHC), Dhahran, Saudi Arabia
Author_xml	– sequence: 1 givenname: Thamer H surname: Al-Khouzaie fullname: Al-Khouzaie, Thamer H email: thamer.khouzath@aramco.com.sa organization: ARAMCO, Dhahran, Saudi Arabia. thamer.khouzath@aramco.com.sa – sequence: 2 givenname: Mohamad F surname: Dawamneh fullname: Dawamneh, Mohamad F – sequence: 3 givenname: Albader M surname: Hazmi fullname: Hazmi, Albader M
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Cites_doi	10.1097/QAD.0b013e3282f08c5a 10.1016/j.jpeds.2004.09.023 10.1186/1752-1947-3-74 10.5858/2002-126-1064-AFAOP 10.1038/modpathol.3800247 10.1097/01.rti.0000168600.78213.85 10.1111/j.1440-1843.2010.01845.x 10.1016/S0873-2159(15)30453-0 10.3904/kjim.2009.24.2.156 10.1111/j.1440-1827.2010.02586.x 10.1016/j.rmed.2009.07.009
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SubjectTerms	Acute Disease Arthralgia - etiology Biopsy Blood tests Case Report Consolidation Cryptogenic Organizing Pneumonia - diagnosis Cryptogenic Organizing Pneumonia - drug therapy Cryptogenic Organizing Pneumonia - pathology Dyspnea Dyspnea - etiology Family medical history Fever Glucocorticoids - therapeutic use HIV Human immunodeficiency virus Humans Leukemia Lungs Male Medical imaging Middle Aged Neutrophils Pathology Patients Pneumonia Prednisone - therapeutic use Severe acute respiratory syndrome Stem cells Tomography, X-Ray Computed Transplants & implants Treatment Outcome
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Title	Acute fibrinous and organizing pneumonia
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