Acute fibrinous and organizing pneumonia

• Published in: Annals of Saudi medicine Vol. 33; no. 3; pp. 301 - 303
• Main Authors: Al-Khouzaie, Thamer H, Dawamneh, Mohamad F, Hazmi, Albader M
• Format: Journal Article
• Language: English
• Published: Saudi Arabia KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE 01-05-2013; King Faisal Specialist Hospital and Research Centre
• Subjects: Acute Disease; Arthralgia - etiology; Biopsy; Blood tests; Case Report; Consolidation; Cryptogenic Organizing Pneumonia - diagnosis; Cryptogenic Organizing Pneumonia - drug therapy; Cryptogenic Organizing Pneumonia - pathology; Dyspnea; Dyspnea - etiology; Family medical history; Fever; Glucocorticoids - therapeutic use; HIV; Human immunodeficiency virus; Humans; Leukemia; Lungs; Male; Medical imaging; Middle Aged; Neutrophils; Pathology; Patients; Pneumonia; Prednisone - therapeutic use; Severe acute respiratory syndrome; Stem cells; Tomography, X-Ray Computed; Transplants & implants; Treatment Outcome; Saudi Arabia; Singapore
• ISSN: 0256-4947; 0975-4466
• DOI: 10.5144/0256-4947.2013.301

A 45-year-old man presented with malaise, arthralgia, and dyspnea. The chest CT scan showed bilateral patchy consolidation in the lower lobes. A lung biopsy revealed intra-alveolar fibrin "balls" deposits and focal features of organizing pneumonia, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). The patient had a good clinical course after treatment with prednisone. We report this case of idiopathic AFOP and review the published studies on this newly recognized clinicopathological entity that is still underdiagnosed and underreported.