Characteristics of children hospitalized with dengue fever in an outbreak in Rio de Janeiro, Brazil

• Published in: Transactions of the Royal Society of Tropical Medicine and Hygiene Vol. 105; no. 10; pp. 601 - 603
• Main Authors: Giraldo, Diana, Sant’Anna, Clemax, Périssé, André Reynaldo Santos, March, Maria de Fatima Pombo, Souza, Ana Paula, Mendes, Analucia, Bonfim, Marcia, Hofer, Cristina B.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01-10-2011; Royal Society of Tropical Medicine and Hygiene; Oxford University Press
• Subjects: Abdominal pain; Abdominal Pain - virology; Adolescent; Arboviroses; Biological and medical sciences; Brazil; Brazil - epidemiology; Child; Child, Preschool; Children; Cohort Studies; Dengue; Dengue - epidemiology; Dengue fevers; Dengue Virus - pathogenicity; Disease Outbreaks; Female; Freshwater; General aspects; Hospitalization; Human viral diseases; Humans; Incidence; Infant; Infectious diseases; Lethargy; Lethargy - virology; Male; Medical sciences; Multivariate Analysis; Retrospective Studies; Risk Factors; Severity of Illness Index; Tropical viral diseases; Viral diseases; South America; Brazil; America; Brazil, Rio de Janeiro; Brazil; Abdominal pain; Lethargy; Children; Dengue; Human; Epidemic; Hospitalization; Abdomen; Infection; Pain; Characteristics; Viral disease; Arbovirus disease; Tropical medicine; Child
• ISSN: 0035-9203; 1878-3503
• DOI: 10.1016/j.trstmh.2011.07.007

During a dengue epidemic in Rio de Janeiro in 2007–2008 the Instituto de Puericultura e Pediatria Martagão Gesteira Hospital was a reference for admitted children. The World Health Organization (WHO) considered several manifestations as warning signs of severe dengue This is a retrospective cohort study of all children admitted with dengue fever. Clinical variables considered warning signs by WHO were evaluated in the multivariate analysis, to investigate if they were independently associated with severe dengue.
One hundred and eighty one children were admitted, aged from 4 months to 15 years; 30 were classified as severe dengue. Abdominal pain (OR
=
2.63, 95% CI1.06–6.53) and lethargy (OR
=
3.40, 95% CI 1.45–7.99) were independently associated with severe dengue.