Single-Cell Analysis of Foot-and-Mouth Disease Virus

With the rapid development of single-cell technologies, the mechanisms underlying viral infections and the interactions between hosts and viruses are starting to be explored at the single-cell level. The foot-and-mouth-disease (FMD) virus (FMDV) causes an acute and persistent infection that can resu...

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Published in:Frontiers in microbiology Vol. 11; p. 361
Main Authors: Wang, Hailong, Xin, Xiu, Zheng, Congyi, Shen, Chao
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 05-03-2020
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Summary:With the rapid development of single-cell technologies, the mechanisms underlying viral infections and the interactions between hosts and viruses are starting to be explored at the single-cell level. The foot-and-mouth-disease (FMD) virus (FMDV) causes an acute and persistent infection that can result in the break-out of FMD, which can have serious effects on animal husbandry. Single-cell techniques have emerged as powerful approaches to analyze virus infection at the resolution of individual cells. In this review, the existing single-cell studies examining FMDV will be systematically summarized, and the central themes of these studies will be presented.
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This article was submitted to Virology, a section of the journal Frontiers in Microbiology
Reviewed by: Anna Kloc, University of New Haven, United States; Ronald Dijkman, University of Bern, Switzerland
Edited by: Juan-Carlos Saiz, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Spain
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2020.00361