Challenges and Management of Acute Coronary Syndrome in Cancer Patients

Cancer and cardiovascular disease are the leading causes of mortality in the world. The prevalence of cardiovascular risk factors and coronary artery disease in cancer patients is elevated, and it is associated with high mortality. Several mechanisms, such as the proinflammatory and procoagulant sta...

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Bibliographic Details
Published in:	Frontiers in cardiovascular medicine Vol. 8; p. 590016
Main Authors:	Costa, Isabela Bispo Santos da Silva, Andrade, Fernanda Thereza de Almeida, Carter, Diego, Seleme, Vinicius B, Costa, Maycon Santos, Campos, Carlos M, Hajjar, Ludhmila Abrahão
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 09-06-2021
Subjects:	acute coronary syndrome cancer cardio oncology cardiotoxicity Cardiovascular Medicine coronary disease cardio oncology coronary disease cardiotoxicity cancer acute coronary syndrome
Online Access:	Get full text
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Summary:	Cancer and cardiovascular disease are the leading causes of mortality in the world. The prevalence of cardiovascular risk factors and coronary artery disease in cancer patients is elevated, and it is associated with high mortality. Several mechanisms, such as the proinflammatory and procoagulant states present in cancer patients, may contribute to these scenarios. Oncological therapy can predispose patients to acute thrombosis, accelerated atherosclerosis and coronary spasm. Treatment decisions must be individualized and based on the cancer history and balancing bleeding and thrombosis risks.
Bibliography:	Reviewed by: Sherry-Ann Brown, Mayo Clinic, United States; Irma Bisceglia, San Camillo-Forlanini Hospital, Italy This article was submitted to Cardio-Oncology, a section of the journal Frontiers in Cardiovascular Medicine Edited by: Reto Asmis, Wake Forest School of Medicine, United States
ISSN:	2297-055X 2297-055X
DOI:	10.3389/fcvm.2021.590016