Osteoma cutis in pseudohypoparathyroidism

• Published in: Clinical and experimental dermatology Vol. 31; no. 2; pp. 225 - 227
• Main Authors: Sethuraman, G., Malhotra, A. K., Khaitan, B. K., Kumar, R., Sharma, V. K., Kabra, M., Singh, M. K.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-03-2006; Blackwell; Oxford University Press
• Subjects: Biological and medical sciences; Bone Neoplasms - complications; Bone Neoplasms - diagnosis; Child; Dermatology; Endocrinopathies; Humans; Male; Medical sciences; Non tumoral diseases. Target tissue resistance. Benign neoplasms; Osteoma - complications; Osteoma - diagnosis; Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases); Pseudohypoparathyroidism - complications; Pseudohypoparathyroidism - diagnosis; Skin Neoplasms - complications; Skin Neoplasms - diagnosis; Endocrinopathy; Human; Case study; Skin disease; Association; Dermatology; Osteoma; Diseases of the osteoarticular system; Pseudohypoparathyroidism; Skin; Child; Genetic disease
• ISSN: 0307-6938; 1365-2230
• DOI: 10.1111/j.1365-2230.2005.02048.x

Summary
Osteoma cutis is the formation of normal bone in the skin. Primary osteoma cutis occurs de novo, whereas the secondary type develops in association with the underlying inflammatory, tumorous or traumatic conditions. Primary osteoma cutis is also associated with Albright's hereditary osteodystrophy (AHO), which can include hypocalcaemic‐type pseudohypoparathyroidism (also known as pseudohypoparathyroidism type Ia) or normocalcaemic‐type pseudohypoparathyroidism (also known as pseudopseudohypoparathyroidism). We describe a case of osteoma cutis in a 7‐year‐old boy who had cutaneous, biochemical and phenotypic features of pseudohypoparathyroidism type Ia and AHO.