Diastolic heart failure in older people – myth or lost tribe?

• Published in: Clinical medicine (London, England) Vol. 2; no. 6; pp. 539 - 543
• Main Authors: Baxter, AJ, Gray, CS
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-11-2002; Royal College of Physicians
• Subjects: Aged; congestive heart failure; Diagnosis, Differential; Diastole; Echocardiography; Heart Failure - diagnosis; Heart Failure - etiology; Heart Failure - physiopathology; Heart Failure - therapy; Humans; left ventricular dysfunction; Original Paper; Risk Factors; Ventricular Dysfunction, Left - complications; Ventricular Dysfunction, Left - diagnosis; Ventricular Dysfunction, Left - physiopathology; Ventricular Dysfunction, Left - therapy; congestive heart failure; left ventricular dysfunction; diastole
• ISSN: 1470-2118; 1473-4893
• DOI: 10.7861/clinmedicine.2-6-539

Left ventricular diastolic dysfunction occurs due to a variable combination of abnormal myocardial relaxation and reduced ventricular compliance. The diagnosis of diastolic congestive heart failure is controversial. Some studies suggest that up to one-third of older people with symptomatic congestive heart failure (CHF) have echocardiograph evidence of diastolic dysfunction. Other authors have suggested the comorbid diseases often found in persons with suspected diastolic CHF explain the patient’s symptoms and hence diastolic CHF is a misdiagnosis in many cases. Many of the characteristic echo features of diastolic dysfunction occur in normal ageing hearts. Unlike in systolic CHF, evidence for disease modifying treatment is lacking. Clinical trials currently in progress to determine the effectiveness of ACE inhibitors and angiotensin II receptor antagonists in the management of diastolic CHF may clarify the prognosis and management of this condition.