Anti-cariogenic effects of polyphenols from plant stimulant beverages (cocoa, coffee, tea)

• Published in: Fitoterapia Vol. 80; no. 5; pp. 255 - 262
• Main Authors: Ferrazzano, Gianmaria F., Amato, Ivana, Ingenito, Aniello, De Natale, Antonino, Pollio, Antonino
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01-07-2009; Elsevier
• Subjects: Anti-Bacterial Agents - pharmacology; Beverages; Biofilms - drug effects; Biological and medical sciences; Cacao - chemistry; Camellia sinensis - chemistry; Central Nervous System Stimulants - pharmacology; Cocoa; Coffea - chemistry; Coffee; Dental caries; Dental Caries - prevention & control; Flavonoids - pharmacology; General pharmacology; Magnoliopsida - chemistry; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Phenols - pharmacology; Plant Extracts - chemistry; Plant Extracts - pharmacology; Polyphenols; Streptococcus - drug effects; Tea; Polyphenols; Tea; Dental caries; Coffee; Cocoa; Stomatology; Pharmacognosy; Dental disease; Dental carie; Stimulant plant; Medicinal plant; Polyphenol; Plant origin; Phenols; Beverage
• ISSN: 0367-326X; 1873-6971
• DOI: 10.1016/j.fitote.2009.04.006

Polyphenols occurring in cocoa, coffee and tea can have a role in the prevention of cariogenic processes, due to their antibacterial action. Cocoa polyphenol pentamers significantly reduce biofilm formation and acid production by
Streptococcus mutans and
S. sanguinis. In the same way, trigonelline, caffeine and chlorogenic acid occurring in green and roasted coffee interfere with
S. mutans adsorption to saliva-coated hydroxyapatite beads. Studies carried out on green, oolong and black tea indicate that tea polyphenols exert an anti-caries effect via an anti-microbial mode-of-action, and galloyl esters of (−)-epicatechin, (−)-epigallocatechin and (−)-gallocatechin show increasing antibacterial activities. The anti-cariogenic effects against α-haemolytic streptococci showed by polyphenols from cocoa, coffee, and tea suggest further studies to a possible application of these beverages in the prevention of pathogenesis of dental caries.
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