A review on Trichomonas vaginalis infections in women from Africa

• Published in: Southern African journal of infectious diseases Vol. 36; no. 1; pp. e1 - e9
• Main Authors: Mabaso, Nonkululeko, Abbai, Nathlee S
• Format: Journal Article
• Language: English
• Published: African Online Scientific Information Systems (Pty) Ltd t/a AOSIS 2021; AOSIS
• Subjects: africa; Cervical cancer; Database searching; drug resistance; Epidemiology; health complications; Internet/Web search services; Medical research; Medicine, Experimental; Metronidazole; Online searching; Pregnant women; Review; Sexually transmitted diseases; trichomonas vaginalis; Kenya; South Africa; Sub-Saharan Africa
• ISSN: 2312-0053; 2313-1810
• DOI: 10.4102/sajid.v36i1.254

Background Trichomoniasis is the most common sexually transmitted infection (STI) with an estimated annual incidence of 276.4 million cases globally and about 30 million cases in sub-Saharan Africa. Trichomoniasis has been found to be associated with various health complications including pelvic inflammatory disease (PID), significant pregnancy complications, cervical cancer, prostatitis, infertility and the acquisition of human immunodeficiency virus (HIV). Aim Despite being a highly prevalent infection in the African continent, there is no review article published that solely focusses on Trichomonas vaginalis (T. vaginalis) infections in women from Africa. This review aims to fill this gap in the literature. Method An electronic search of online databases was used to identify and extract relevant research articles related to the epidemiology, health complications and treatment associated with T. vaginalis in women from Africa. Results Within the African continent, South Africa has reported the highest prevalence rate for this infection. A combination of sociodemographic, behavioural and biological factors has been shown to be associated with infection. Trichomonas vaginalis infection is associated with the acquisition of HIV, cervical cancer and PIDs in various female populations across the continent. Emerging patterns of resistance to metronidazole have been reported in women from South Africa. Currently, there is no effective vaccine against this pathogen despite efforts at vaccine development. Conclusion Based on the high prevalence and health consequences associated with T. vaginalis, there is a need for improved screening programmes that will lead to early diagnosis, detection of asymptomatic infections and effective treatment regimens.