Pinoresinol from Ipomoea cairica cell cultures

Ipomoea cairica cell cultures produced a tetrahydrofuran lignan, (+)-pinoresinol, identified by UV, IR, MS and NMR methods, not yet found in the intact plant, and new in the Convolvulaceae family. Pinoresinol was found to have antioxidant and Ca2+ antagonist properties. As it could be requested for...

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Bibliographic Details
Published in:	Natural product letters Vol. 16; no. 5; pp. 359 - 363
Main Authors:	Páska, Csilla, Innocenti, Gabbriella, Ferlin, Mariagrazia, Kunvári, Mónika, László, Miklós
Format:	Journal Article
Language:	English
Published:	England 01-10-2002
Subjects:	Antioxidants - chemistry Antioxidants - isolation & purification Antioxidants - metabolism Antioxidants - pharmacology Calcium - antagonists & inhibitors Cells, Cultured Convolvulaceae Culture Media, Conditioned - chemistry Furans Ipomoea - cytology Ipomoea - metabolism Ipomoea cairica Lignans - chemistry Lignans - isolation & purification Lignans - metabolism Lignans - pharmacology Magnetic Resonance Spectroscopy Molecular Structure
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Summary:	Ipomoea cairica cell cultures produced a tetrahydrofuran lignan, (+)-pinoresinol, identified by UV, IR, MS and NMR methods, not yet found in the intact plant, and new in the Convolvulaceae family. Pinoresinol was found to have antioxidant and Ca2+ antagonist properties. As it could be requested for its biological activity, we examined the possibility to raise the pinoresinol yield of I. cairica cultures, as well as we continued investigations on lignans' response to optimization.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1057-5634 1478-6419
DOI:	10.1080/1057530290033123