Higher sea fish intake is associated with greater bone mass and lower osteoporosis risk in postmenopausal Chinese women

• Published in: Osteoporosis international Vol. 21; no. 6; pp. 939 - 946
• Main Authors: Chen, Y.-m, Ho, S. C, Lam, S. S
• Format: Journal Article
• Language: English
• Published: London London : Springer-Verlag 01-06-2010; Springer-Verlag; Springer; Springer Nature B.V
• Subjects: Animals; Anthropometry; Biological and medical sciences; Bone density; Bone Density - physiology; Bone mineral content; Diet; Diet - statistics & numerical data; Diseases of the osteoarticular system; Endocrinology; Epidemiologic Methods; Feeding Behavior; Female; Fish; Fishes; Hong Kong - epidemiology; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Medicine; Medicine & Public Health; Menopause; Middle Aged; Original Article; Orthopedics; Osteoarticular system. Muscles; Osteoporosis; Osteoporosis, Postmenopausal - epidemiology; Osteoporosis, Postmenopausal - physiopathology; Osteoporosis, Postmenopausal - prevention & control; Osteoporosis. Osteomalacia. Paget disease; Postmenopausal women; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Rheumatology; Risk factors; Seafood - statistics & numerical data; Women; China; Bone mineral content; Osteoporosis; Fish; Bone density; Postmenopausal women; Human; Diseases of the osteoarticular system; Rheumatology; Bone mass; Risk factor; Postmenopause; Bone mineral density; Woman
• ISSN: 0937-941X; 1433-2965
• DOI: 10.1007/s00198-009-1029-4

Summary We examined the cross-sectional association of the intakes of different types of fishes with bone mass and osteoporosis risk in postmenopausal Chinese women. We found that higher intake of sea fish is independently associated with greater bone mass and lower osteoporosis risk among postmenopausal Chinese women. Introduction Fish contains many important nutrients that are beneficial on bone health, but limited data on the relationship between fish intake and bone health are available. We examined the association of the intakes of different types of fishes with bone mineral density (BMD) and bone mineral content (BMC) and osteoporosis risk. Methods This population-based cross-sectional study was conducted among 685 postmenopausal Chinese women. Habitual dietary intakes were assessed using food frequency questionnaire. BMD and BMC at the whole body, lumbar spine, and left hip were measured with dual-energy x-ray absorptiometry. Results After adjusting for the potential confounders, we observed dose-dependent relations between sea fish intake and BMDs, BMCs, and osteoporosis risk; the mean BMDs were 3.2-6.8% higher, and BMCs 5.1-9.4% higher in the top quintile groups (Q5) of sea fish intake than in the bottom quintile (Q1) at the whole body and hip sites (p < 0.05); the odds ratios (95% confidence interval (CI)) for osteoporosis (T-score < −2.5) in Q5 were 0.23 (0.08-0.66), 0.12 (0.03-0.59), and 0.06 (0.01-0.44) compared with those in Q1 at the whole body, total hip, and femur neck, respectively. No independent association between consumption of freshwater fish or shellfish and bone mass was observed. Conclusion Higher intake of sea fish is independently associated with greater bone mass and lower osteoporosis risk among postmenopausal Chinese women.