Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates

• Published in: The Journal of experimental zoology Vol. 292; no. 5; pp. 430 - 434
• Main Authors: Duggan, Annemarie E., Marie Jr, Ronald Ste, Callard, Ian P.
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01-04-2002
• Subjects: Adaptation, Physiological; Animals; Antibodies; Anura; Blotting, Western; Carassius auratus; CD36 Antigens - biosynthesis; Chickens; Cholesterol - metabolism; Chondrichthyes; Chrysemys picta; Electrophoresis, Polyacrylamide Gel; Female; Goldfish; Membrane Proteins; Mice; Ovary - growth & development; Ovary - physiology; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Sharks; Tissue Distribution; Turtles - physiology
• ISSN: 0022-104X; 1097-010X
• DOI: 10.1002/jez.10067

In this study, the tissue distribution of the expression of an HDL‐receptor (SR‐BI; Scavenger Receptor Class B Type I) was investigated in the turtle using an antiserum to murine SR‐BI. Several turtle tissues including liver, heart, small intestine, kidney, oviduct, ovary, and testis were shown to express an 82 kDa membrane protein. In addition, SR‐BI expression in livers of other nonmammalian species such as the chicken, frog, goldfish, shark, and skate is also reported. Ovarian SR‐BI expression varies seasonally in the turtle as do plasma levels of apoA‐I and cholesterol ester. It is possible that changing levels of SR‐BI, the receptor for apoA‐I, is physiologically relevant to the demands of the turtle ovarian cycle and cholesterol distribution. J. Exp. Zool. 292:430–434, 2002. © 2002 Wiley‐Liss, Inc.