Wastewater-based epidemiology: A Brazilian SARS-COV-2 surveillance experience

• Published in: Journal of environmental chemical engineering Vol. 10; no. 5; p. 108298
• Main Authors: de Freitas Bueno, Rodrigo, Claro, Ieda Carolina Mantovani, Augusto, Matheus Ribeiro, Duran, Adriana Feliciano Alves, Camillo, Lívia de Moraes Bomediano, Cabral, Aline Diniz, Sodré, Fernando Fabriz, Brandão, Cristina Celia Silveira, Vizzotto, Carla Simone, Silveira, Rafaella, de Melo Mendes, Geovana, Arruda, Andrea Fernandes, de Brito, Núbia Natália, Machado, Bruna Aparecida Souza, Duarte, Gabriela Rodrigues Mendes, de Lourdes Aguiar-Oliveira, Maria
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01-10-2022
• Subjects: Brazil; COVID-19; SARS-CoV-2; Sewage; Wastewater surveillance; Wastewater-based epidemiology; COVID-19; Brazil; SARS-CoV-2; Sewage; Wastewater surveillance; Wastewater-based epidemiology
• ISSN: 2213-3437; 2213-2929; 2213-3437
• DOI: 10.1016/j.jece.2022.108298

Since 2020, developed countries have rapidly shared both publicly and academically relevant wastewater surveillance information. Data on SARS-CoV-2 circulation is pivotal for guiding public health policies and improving the COVID-19 pandemic response. Conversely, low- and middle-income countries, such as Latin America and the Caribbean, showed timid activities in the Wastewater-Based Epidemiology (WBE) context. In these countries, isolated groups perform viral wastewater monitoring, and the data are unevenly shared or accessible to health agencies and the scientific community. This manuscript aims to highlight the relevance of a multiparty effort involving research, public health, and governmental agencies to support usage of WBE methodology to its full potential during the COVID-19 pandemic as part of a joint One Health surveillance approach. Thus, in this study, we explored the results obtained from wastewater surveillance in different regions of Brazil as a part of the COVID-19 Wastewater Monitoring Network ANA (National Water Agency), MCTI (Ministry of Science, Technology, and Innovations) and MS (Ministry of Health). Over the epidemiological weeks of 2021 and early 2022, viral RNA concentrations in wastewater followed epidemiological trends and variations. The highest viral loads in wastewater samples were detected during the second Brazilian wave of COVID-19. Corroborating international reports, our experience demonstrated usefulness of the WBE approach in viral surveillance. Wastewater surveillance allows hotspot identification, and therefore, early public health interventions. In addition, this methodology allows tracking of asymptomatic and oligosymptomatic individuals, who are generally underreported, especially in emerging countries with limited clinical testing capacity. Therefore, WBE undoubtedly contributes to improving public health responses in the context of this pandemic, as well as other sanitary emergencies.
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•WBE should be implemented as part of COVID-19 pandemic response in emerging countries.•The wastewater surveillance data from four Brazilian municipalities are presented.•The emergence of the Omicron variant (B.1.1.529) caused a large increase in clinical cases in early 2022.