Design and validity of a miniaturized open-field aberrometer

• Published in: Journal of cataract and refractive surgery Vol. 39; no. 1; pp. 36 - 40
• Main Authors: Bhatt, Uday K., MD, Sheppard, Amy L., PhD, Shah, Sunil, FRCS, Dua, Harmindar Singh, FRCS, Mihashi, Toshifumi, PhD, Yamaguchi, Tatsuo, PhD, Wolffsohn, James S., PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-01-2013
• Subjects: Aberrometry - instrumentation; Adult; Corneal Wavefront Aberration - diagnosis; Equipment Design; Female; Humans; Male; Microscopy - instrumentation; Ophthalmology; Predictive Value of Tests; Refractive Errors - diagnosis; Reproducibility of Results; Sensitivity and Specificity; Young Adult
• ISSN: 0886-3350; 1873-4502
• DOI: 10.1016/j.jcrs.2012.08.052

Purpose To design and validate a new miniaturized open-field wavefront device that can be attached to an ophthalmic surgical microscope or slitlamp. Setting Solihull Hospital and Aston University, Birmingham, United Kingdom. Design Comparative noninterventional study. Methods The dynamic range of the Aston aberrometer was assessed using a calibrated model eye. The validity was compared with that of a conventional desk-mounted Hartmann-Shack aberrometer (Topcon KR1W) in dilated eyes. The instruments were used in random order, with measurements repeated 5 times to assess intrasession repeatability. Results The open-field aberrometer had a large dynamic range of at least +21.0 diopters (D) to −25.0 D. It gave similar measurements to the conventional aberrometer for mean spherical equivalent (SE) (mean difference 0.02 D ± 0.49 [95% confidence interval]; correlation r  = 0.995; P <.001), astigmatic components (J0: 0.02 ± 0.15 D; r = 0.977, P <.001; J45: 0.03 ± 0.28, r = 0.666, P <.001), and higher-order aberration (HOA) root mean square (RMS) (0.02 ± 0.20 D, r = 0.620, P <.001). Intraclass correlation coefficient assessments of intrasession repeatability were excellent (SE = 1.000, P <.001; J0 = 0.998, P <.001; J45 = 0.980, P <.01; HOA RMS = 0.961, P <.001). Conclusions The new aberrometer gave valid, repeatable measurements of refractive error and HOAs over a large range. It can measure continuously, thus providing direct feedback on the optical status of the visual system to surgeons during intraocular lens implantation and corneal surgery. Financial Disclosure The Aston aberrometer is jointly patented by Topcon Corp. and Prof. Wolffsohn. Drs. Mihashi and Yamaguchi are employees of Topcon Corp., Tokyo, Japan. No other author has a financial or proprietary interest in any material or method mentioned.