Brenner tumors

• Published in: British journal of radiology Vol. 95; no. 1130; p. 20210687
• Main Authors: Costeira, Filipa de Sousa, Félix, Ana, Cunha, Teresa Margarida
• Format: Journal Article
• Language: English
• Published: England The British Institute of Radiology 01-02-2022
• Subjects: Brenner Tumor - diagnostic imaging; Brenner Tumor - pathology; Cystadenofibroma - diagnostic imaging; Diagnosis, Differential; Female; Fibroma - diagnostic imaging; Fibroma - pathology; Humans; Leiomyoma - diagnostic imaging; Magnetic Resonance Imaging; Ovarian Neoplasms - diagnostic imaging; Ovarian Neoplasms - pathology; Pictorial Review; Rare Diseases - diagnostic imaging; Rare Diseases - pathology; Thecoma - diagnostic imaging; Thecoma - pathology; Tomography, X-Ray Computed; Ultrasonography
• ISSN: 0007-1285; 1748-880X
• DOI: 10.1259/bjr.20210687

Brenner tumors are rare ovarian neoplasms composed of ovarian transition cells surrounded by dense fibrous tissue. Most of them are small tumors (<2 cm), detected incidentally in asymptomatic women. Its predominantly fibrous content results in relatively low signal on
weighted images, establishing differential diagnosis with ovarian fibroma and thecoma. Their imaging features are very similar, the differentiation is based on secondary characteristics, such as signs or symptoms of estrogen excess and the presence of a second ovarian neoplasm, which has been reported in up to 30% of patients with Brenner tumor. Although originally thought to be universally benign, there have been scattered reports in the past decades of borderline and malignant forms of Brenner tumors.