Stationary pattern adaptation and the early components in human visual evoked potentials

• Published in: Electroencephalography and clinical neurophysiology Vol. 77; no. 3; p. 190
• Main Authors: Hudnell, H K, Boyes, W K, Otto, D A
• Format: Journal Article
• Language: English
• Published: Ireland 01-05-1990
• Subjects: Adaptation, Ocular - physiology; Analysis of Variance; Evoked Potentials, Visual - physiology; Female; Humans; Male; Pattern Recognition, Visual; Retina - physiology
• ISSN: 0013-4694
• DOI: 10.1016/0168-5597(90)90037-E

Pattern-onset visual evoked potentials were elicited from humans by sinusoidal gratings of 0.5, 1, 2 and 4 cpd (cycles/degree) following adaptation to a blank field or one of the gratings. The wave forms recorded after blank field adaptation showed an early positive component, P0, which decreased in amplitude with spatial frequency, whereas the immediately succeeding negative component, N1, increased in amplitude with spatial frequency. P0 and N1 components of comparable size were recorded at 1 cpd. Stationary pattern adaptation to a grating of the same spatial frequency as the test grating significantly reduced N1 amplitude at 4, 2 and 1 cpd. The N1 component elicited at 4 cpd was attenuated in log-linear fashion as the spatial frequency of the adaptation grating increased. P0, on the other hand, was unaffected by stationary pattern adaptation at all combinations of test and adapting spatial frequencies, although P0 amplitude is known to be attenuated by adaptation to a drifting grating. Since N1, but not P0, was significantly attenuated following adaptation and testing at 1 cpd, it was concluded that the neurons generating these components are functionally distinct. The use of a common adaptation grating discounted the possibility that N1, but not P0, was affected due to a difference in the rates of retinal image modulation caused by eye movements made while viewing adaptation gratings of different spatial frequencies. The neurons generating N1 were adapted at a lower rate of retinal image modulation than that apparently required for adaptation of the neurons generating P0, which suggests a difference between these neurons in the rate of stimulus modulation necessary for activation.