Presence of hepcidin-25 in biological fluids: Bile,ascitic and pleural fluids

Presence of hepcidin-25 in biological fluids: Bile,ascitic and pleural fluids

AIM: To examine body fluids such as ascitic fluid (AF),saliva,bile and pleural effusions for the presence of hepcidin using a novel radioimmunoassay (RIA).METHODS: Serum samples were collected from 25 healthy volunteers (mean age: 36 ± 11.9 years,11 males,14 females).In addition bile was obtained fr...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG Vol. 16; no. 17; pp. 2129 - 2133
Main Authors: Arnold, Jayantha, Sangwaiya, Arvind, Manglam, Vijay, Geoghegan, Frank, Thursz, Mark, Busbridge, Mark
Format: Journal Article
Language:English
Published: United States Baishideng 07-05-2010
Subjects:
Adult
Aged
Aged, 80 and over
Antimicrobial Cationic Peptides - blood
Antimicrobial Cationic Peptides - metabolism
Ascitic Fluid - metabolism
Bile - metabolism
Brief
Case-Control Studies
Female
Hepcidins
Humans
Male
Middle Aged
Pleural Effusion - metabolism
Prospective Studies
Radioimmunoassay - methods
Saliva - metabolism
Young Adult
Exudates
Antimicrobial peptides
Hepcidin in biological fluids
Hepcidin
Hepcidin in ascitic fluid
Hepcidin assay
Bile
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Summary:AIM: To examine body fluids such as ascitic fluid (AF),saliva,bile and pleural effusions for the presence of hepcidin using a novel radioimmunoassay (RIA).METHODS: Serum samples were collected from 25 healthy volunteers (mean age: 36 ± 11.9 years,11 males,14 females).In addition bile was obtained from 12 patients undergoing endoscopic retrograde cholangiopancreatography (mean age: 66.9 ± 16.7 years,M:F = 5:7).Saliva was collected from 17 healthy volunteers (mean age: 35 ± 9.9 years,M:F = 8:9).Pleural and AF...
Bibliography:Exudates
14-1219/R
Antimicrobial peptides
Hepcidin in biological fluids
R318.0
Hepcidin; Hepcidin assay; Hepcidin in biological fluids; Hepcidin in ascitic fluid; Bile; Exudates; Antimicrobial peptides
Hepcidin
Hepcidin in ascitic fluid
Hepcidin assay
Bile
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Author contributions: Arnold J designed, supervised, co-authored and proof read the manuscript; Sangwaiya A designed, led laboratory work, wrote the paper and edited the manuscript; Manglam V recruited the patients, participated in research and helped write the manuscript; Geoghegan F helped in analysis of samples and co-authored the manuscript; Thursz M edited and proof read the manuscript; Busbridge M helped with laboratory work and help write the manuscript.
Telephone: +44-208-9675513 Fax: +44-208-9675083
Correspondence to: Jayantha Arnold, Professor, Department of Gastroenterology, Ealing Hospital NHS Trust, Uxbridge Road, London UB1 3HW, United Kingdom. jayanthaarnold@hotmail.com
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v16.i17.2129