Multinucleation and cleavage of embryos derived from in vitro-matured oocytes

In patients with polycystic ovary syndrome (PCOS), the proportion of optimal embryos-blastomere number and fragmentation rate-derived from in vitro-matured oocytes after the hCG priming protocol was higher (43.3%) than the proportion of optimal embryos derived from oocyte in vitro maturation with th...

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Bibliographic Details
Published in:	Fertility and sterility Vol. 86; no. 2; p. 487
Main Authors:	Vlaisavljević, Veljko, Cizek-Sajko, Mojca, Kovac, Vilma
Format:	Journal Article
Language:	English
Published:	United States 01-08-2006
Subjects:	Adult Blastocyst - cytology Blastocyst - physiology Blastomeres - cytology Blastomeres - ultrastructure Cell Count Cell Nucleus - ultrastructure Cells, Cultured Chorionic Gonadotropin - pharmacology Cleavage Stage, Ovum - physiology Female Fertilization in Vitro Follicle Stimulating Hormone - pharmacology Humans Infertility, Female - etiology Infertility, Female - therapy Oocytes - drug effects Oogenesis Polycystic Ovary Syndrome - complications Pregnancy Pregnancy Rate Sperm Injections, Intracytoplasmic
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Summary:	In patients with polycystic ovary syndrome (PCOS), the proportion of optimal embryos-blastomere number and fragmentation rate-derived from in vitro-matured oocytes after the hCG priming protocol was higher (43.3%) than the proportion of optimal embryos derived from oocyte in vitro maturation with the FSH priming protocol (11.1%). The embryos derived from in vitro-matured oocytes after the hCG priming protocol also showed a lower incidence of multinucleated blastomeres. Pregnancies were recorded only in the hCG primed patients.
ISSN:	1556-5653
DOI:	10.1016/j.fertnstert.2006.01.026