Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels

Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels

We present a novel chemically cross-linked dextran-poly(ethylene glycol) hydrogel substrate for the preparation of dense vesicle suspensions under physiological ionic strength conditions. These vesicles can be easily diluted for individual study. Modulating the degree of cross-linking within the hyd...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) Vol. 50; no. 16; p. 1953
Main Authors: López Mora, Néstor, Hansen, Jesper S, Gao, Yue, Ronald, Andrew A, Kieltyka, Roxanne, Malmstadt, Noah, Kros, Alexander
Format: Journal Article
Language:English
Published: England 25-02-2014
Subjects:
Cross-Linking Reagents - chemical synthesis
Cross-Linking Reagents - chemistry
Dextrans - chemistry
Ethylene Glycol - chemistry
Hydrogels - chemical synthesis
Hydrogels - chemistry
Osmolar Concentration
Particle Size
Surface Properties
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Summary:We present a novel chemically cross-linked dextran-poly(ethylene glycol) hydrogel substrate for the preparation of dense vesicle suspensions under physiological ionic strength conditions. These vesicles can be easily diluted for individual study. Modulating the degree of cross-linking within the hydrogel network results in tuning of the vesicle size distribution.
ISSN:1364-548X
DOI:10.1039/c3cc49144g