Environmental persistence of OXA-48–producing Klebsiella pneumoniae in a French intensive care unit

• Published in: American journal of infection control Vol. 44; no. 3; pp. 366 - 368
• Main Authors: Pantel, Alix, PharmD, Richaud-Morel, Brigitte, PharmD, Cazaban, Michel, MD, Bouziges, Nicole, MD, Sotto, Albert, MD, PhD, Lavigne, Jean-Philippe, MD, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-03-2016; Mosby-Year Book, Inc; Elsevier
• Subjects: Aged; Aged, 80 and over; beta-Lactamases - analysis; Carbapenemase; Cross Infection - epidemiology; Disease control; Disease Outbreaks; Enterobacteriaceae; Environment; Environmental Microbiology; Epidemiology; France; Genotype; Gram-negative bacteria; Human health and pathology; Humans; Infection Control; Infectious Disease; Infectious diseases; Intensive care; Intensive Care Units; Klebsiella Infections - epidemiology; Klebsiella pneumoniae; Klebsiella pneumoniae - classification; Klebsiella pneumoniae - enzymology; Klebsiella pneumoniae - genetics; Klebsiella pneumoniae - isolation & purification; Life Sciences; Male; Middle Aged; Molecular Typing; OXA-48; Persistence; Santé publique et épidémiologie; France; Persistence; Carbapenemase; Environment; France; OXA-48; Klebsiella pneumoniae; Enterobacteriaceae
• ISSN: 0196-6553; 1527-3296
• DOI: 10.1016/j.ajic.2015.09.021

The spread of carbapenemase-producing Gram-negative rods is an emerging global problem. This study describes the epidemiologic features of an outbreak caused by an environmental reservoir of OXA-48–producing Klebsiella pneumoniae caused by persistence of the bacteria during 20 months in an intensive care unit in France. This report emphasizes the importance of early environmental screening to interrupt the transmission of carbapenemase-producing Enterobacteriaceae.