Association between Bacterial Vaginosis and Expression of Human Immunodeficiency Virus Type 1 RNA in the Female Genital Tract

• Published in: Clinical infectious diseases Vol. 33; no. 6; pp. 894 - 896
• Main Authors: Cu-Uvin, Susan, Hogan, Joseph W., Caliendo, Angela M., Harwell, Joseph, Mayer, Kenneth H., Carpenter, Charles C. J.
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 15-09-2001; University of Chicago Press
• Subjects: Adult; Antiretroviral Therapy, Highly Active; Bacterial vaginosis; Biological and medical sciences; Female; Genitalia; Genitalia, Female - virology; Highly active antiretroviral therapy; HIV; HIV 1; HIV Infections - complications; HIV Infections - drug therapy; HIV Infections - virology; HIV-1 - genetics; HIV-1 - isolation & purification; HIV/AIDS; Human viral diseases; Humans; Infections; Infectious diseases; Medical sciences; Reproductive tract infections; RNA; RNA, Viral - genetics; RNA, Viral - isolation & purification; Vaginal Smears; Vaginitis; Vaginosis, Bacterial - complications; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viruses; Human; Immunopathology; RNA; HIV-1 virus; Genital system; Retroviridae; Vagina; Vaginal diseases; AIDS; Vaginitis; Immune deficiency; Lentivirus; Female genital diseases; Infection; Virus; Viral disease; Risk factor; Female; Human immunodeficiency virus; Colonization
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/322613

We assessed the effect of lower genital tract infections on human immunodeficiency virus type 1 (HIV-1) RNA shedding in the female genital tract. Bacterial vaginosis was significantly associated with HIV-1 RNA expression in the female genital tract of HIV-infected women.