Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients--10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval durin...

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Bibliographic Details
Published in:	Magnetic resonance imaging Vol. 11; no. 5; p. 617
Main Authors:	Flickinger, F W, Allison, J D, Sherry, R M, Wright, J C
Format:	Journal Article
Language:	English
Published:	Netherlands 1993
Subjects:	Adenofibroma - diagnosis Adult Aged Breast Neoplasms - diagnosis Breast Neoplasms - pathology Contrast Media Female Fibrocystic Breast Disease - diagnosis Gadolinium Gadolinium DTPA Humans Magnetic Resonance Imaging - methods Middle Aged Organometallic Compounds Pentetic Acid
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Summary:	Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients--10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.
ISSN:	0730-725X
DOI:	10.1016/0730-725x(93)90002-u