The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurot...

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Bibliographic Details
Published in:	Cytogenetics and cell genetics Vol. 79; no. 3-4; p. 198
Main Authors:	Koehler, M R, Wissinger, B, Gorboulev, V, Koepsell, H, Schmid, M
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-1997
Subjects:	Carrier Proteins - genetics Chaperonin Containing TCP-1 Chaperonins Chromosome Mapping Chromosomes, Human, Pair 6 Heat-Shock Proteins - genetics Humans Molecular Chaperones - genetics Organic Cation Transport Proteins Organic Cation Transporter 2 Polymerase Chain Reaction
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Summary:	Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 genes (SLC22A1, SLC22A2) on chromosome 6q26.
ISSN:	0301-0171
DOI:	10.1159/000134720