Precision Medicine and Obesity

The highly variable response to obesity therapies justifies the search for treatment strategies that are best suited to individual patients to enhance their effectiveness and tolerability via precision medicine. Precision medicine development in recent years has been driven by the emergence of power...

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Bibliographic Details
Published in:Gastroenterology clinics of North America Vol. 50; no. 1; pp. 127 - 139
Main Authors: Hurtado A, Maria Daniela, Acosta, Andres
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-03-2021
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Summary:The highly variable response to obesity therapies justifies the search for treatment strategies that are best suited to individual patients to enhance their effectiveness and tolerability via precision medicine. Precision medicine development in recent years has been driven by the emergence of powerful methods to characterize patients (“omic” assays). Current available information has revealed that there are numerous intermediary processes that contribute to obesity and have provided a framework for partially comprehending the mechanisms behind the heterogeneity of obesity and its clinical consequences. Some of these processes have or are currently being targeted to individualize obesity therapy with some success.
Bibliography:ObjectType-Article-2
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ISSN:0889-8553
1558-1942
DOI:10.1016/j.gtc.2020.10.005